The Drosophila pericentrin-like protein is essential for cilia/flagella function, but appears to be dispensable for mitosis.

Centrosomes consist of a pair of centrioles surrounded by an amorphous pericentriolar material (PCM). Proteins that contain a Pericentrin/AKAP450 centrosomal targeting (PACT) domain have been implicated in recruiting several proteins to the PCM. We show that the only PACT domain protein in Drosophil...

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Main Authors: Martinez-Campos, M, Basto, R, Baker, J, Kernan, M, Raff, J
格式: Journal article
语言:English
出版: 2004