Genomic regulation and molecular pathways of X chromosome inactivation

<p>X chromosome inactivation (XCI) is a process by which one X chromosome in female mammals is silenced to equalise the dosage of X-linked gene expression between XX females and XY males. XCI is initiated by a long non-coding RNA (lncRNA), Xist, expressed from the future inactive X chromosome...

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Bibliographic Details
Main Author: Bowness, JS
Other Authors: Brockdorff, N
Format: Thesis
Language:English
Published: 2021
Subjects: