Virus-like particles as carriers for T-cell epitopes: limited inhibition of T-cell priming by carrier-specific antibodies.

Virus-like particles (VLPs) are able to induce cytotoxic T-cell responses in the absence of infection or replication. This makes VLPs promising candidates for the development of recombinant vaccines. However, VLPs are also potent inducers of B-cell responses, and it is generally assumed that such VL...

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Bibliographic Details
Main Authors: Ruedl, C, Schwarz, K, Jegerlehner, A, Storni, T, Manolova, V, Bachmann, M
Format: Journal article
Language:English
Published: 2005