Virus-like particles as carriers for T-cell epitopes: limited inhibition of T-cell priming by carrier-specific antibodies.
Virus-like particles (VLPs) are able to induce cytotoxic T-cell responses in the absence of infection or replication. This makes VLPs promising candidates for the development of recombinant vaccines. However, VLPs are also potent inducers of B-cell responses, and it is generally assumed that such VL...
Main Authors: | Ruedl, C, Schwarz, K, Jegerlehner, A, Storni, T, Manolova, V, Bachmann, M |
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Format: | Journal article |
Language: | English |
Published: |
2005
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