Endothelial cell Ca2+ increases are independent of membrane potential in pressurized rat mesenteric arteries.

In rat mesenteric arteries, the ability of ACh to evoke hyperpolarization of smooth muscle cells and consummate dilatation relies on an increase in endothelial cell cytosolic free [Ca2+] and activation of Ca2+-activated K+ channels (KCa). The time course of average and spatially organized rises in e...

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Bibliographic Details
Main Authors: McSherry, I, Spitaler, M, Takano, H, Dora, K
Format: Journal article
Language:English
Published: 2005