Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo.
Three closely related mammalian R-Smads, namely Smad1, Smad5 and Smad8, are activated by BMP receptors. Here we have taken a genetic approach to further dissect their possibly unique and/or shared roles during early mouse development. A Smad8.LacZ reporter allele was created to visualize Smad8 expre...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal article |
| Sprog: | English |
| Udgivet: |
2006
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