Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo.

Three closely related mammalian R-Smads, namely Smad1, Smad5 and Smad8, are activated by BMP receptors. Here we have taken a genetic approach to further dissect their possibly unique and/or shared roles during early mouse development. A Smad8.LacZ reporter allele was created to visualize Smad8 expre...

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Những tác giả chính: Arnold, S, Maretto, S, Islam, A, Bikoff, E, Robertson, E
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2006