Selective effects of electrostatic changes in the CD4 CDR-3-like loop on infection by different human immunodeficiency virus type 1 isolates.

The role of the CDR-3-like loop of the first domain of the CD4 molecule in infection by the human immunodeficiency virus type 1 (HIV-1) is controversial. In an attempt to determine whether the strong negative charge in the CDR-3-like loop influences HIV-1 infection we have substituted by mutagenesis...

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Bibliographic Details
Main Authors: Signoret, N, Blanc-Zouaoui, D, Kwong, P, Sattentau, Q
Format: Journal article
Language:English
Published: 1996