Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig
The type and genomic context of cancer mutations depend on their causes. These causes have been characterized using signatures that represent mutation types that co-occur in the same tumours. However, it remains unclear how mutation processes change during cancer evolution due to the lack of reliabl...
| Hauptverfasser: | , , , , , , , , , |
|---|---|
| Weitere Verfasser: | |
| Format: | Journal article |
| Sprache: | English |
| Veröffentlicht: |
Springer Nature
2020
|