Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig
The type and genomic context of cancer mutations depend on their causes. These causes have been characterized using signatures that represent mutation types that co-occur in the same tumours. However, it remains unclear how mutation processes change during cancer evolution due to the lack of reliabl...
主要な著者: | , , , , , , , , , |
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その他の著者: | |
フォーマット: | Journal article |
言語: | English |
出版事項: |
Springer Nature
2020
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