Understanding the molecular pharmacology of vascular calcium-activated chloride channels

Understanding the molecular pharmacology of vascular calcium-activated chloride channels

<p>Calcium-activated chloride channels (CaCCs) are a class of ion channel involved in a multitude of cellular functions. The role of CaCCs is especially well recognised in vascular smooth muscle cells (VSMCs), where CaCCs are activated by agonist-induced Ca2+ release and their opening triggers...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Dinsdale, R
Awduron Eraill:	Tammaro, P
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2021

Eitemau Tebyg

Calcium-Activated Chloride Channels in Myometrial and Vascular Smooth Muscle
gan: Susan Wray, et al.
Cyhoeddwyd: (2021-10-01)

The molecular pharmacology and modulation of the proton-activated chloride channel PAC
gan: Pearson, CL
Cyhoeddwyd: (2023)

Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin
gan: Alexandria N Miller, et al.
Cyhoeddwyd: (2019-01-01)

Molecular pathology of renal chloride channels and calcium metabolism
gan: Thakker, R
Cyhoeddwyd: (2003)

Molecular pharmacology of kidney and inner ear CLC-K chloride channels
gan: Antonella eGradogna, et al.
Cyhoeddwyd: (2010-10-01)

Molecular pharmacology of native and exogenous vascular ion channels
gan: Ta, C
Cyhoeddwyd: (2016)

Activation and inhibition of TMEM16A calcium-activated chloride channels.
gan: Yu-Li Ni, et al.
Cyhoeddwyd: (2014-01-01)

Activation and Inhibition of TMEM16A Calcium-Activated Chloride Channels
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Cyhoeddwyd: (2014)

Cardiac chloride channels: physiology, pharmacology and approaches for identifying novel modulators of activity.
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Cyhoeddwyd: (2000)

TMEM16 proteins: the long awaited calcium-activated chloride channels?
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Cyhoeddwyd: (2009-11-01)

Interspecies diversity of chloride channel regulators, calcium-activated 3 genes.
gan: Lars Mundhenk, et al.
Cyhoeddwyd: (2018-01-01)

The Calcium-Activated Chloride Channel TMEM16A is Inhibitied by Liquiritigenin
gan: Mami Kato, et al.
Cyhoeddwyd: (2021-04-01)

Gating the pore of the calcium-activated chloride channel TMEM16A
gan: Andy K. M. Lam, et al.
Cyhoeddwyd: (2021-02-01)

Permeation Mechanisms in the TMEM16B Calcium-Activated Chloride Channels.
gan: Simone Pifferi
Cyhoeddwyd: (2017-01-01)

TMEM16 proteins: the long awaited calcium-activated chloride channels?
gan: C.A. Flores, et al.

Molecular understanding of calcium permeation through the open Orai channel.
gan: Xiaofen Liu, et al.
Cyhoeddwyd: (2019-04-01)

Shikonin inhibits intestinal calcium-activated chloride channels and prevents rotaviral diarrhea
gan: Yu Jiang, et al.
Cyhoeddwyd: (2016-08-01)

ANO1: More Than Just Calcium-Activated Chloride Channel in Cancer
gan: Saisai Guo, et al.
Cyhoeddwyd: (2022-06-01)

Mechanism of pore opening in the calcium-activated chloride channel TMEM16A
gan: Andy K. M. Lam, et al.
Cyhoeddwyd: (2021-02-01)

A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity
gan: Jason Tien, et al.
Cyhoeddwyd: (2014-06-01)

Calcium-dependent electrostatic control of anion access to the pore of the calcium-activated chloride channel TMEM16A
gan: Andy KM Lam, et al.
Cyhoeddwyd: (2018-10-01)

Calcium-calmodulin does not alter the anion permeability of the mouse TMEM16A calcium-activated chloride channel
gan: Yu, Y, et al.
Cyhoeddwyd: (2014)

Spatial distribution of calcium-gated chloride channels in olfactory cilia.
gan: Donald A French, et al.
Cyhoeddwyd: (2010-01-01)

Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A
gan: Cristina Paulino, et al.
Cyhoeddwyd: (2017-05-01)

Anoctamin Calcium-Activated Chloride Channels May Modulate Inhibitory Transmission in the Cerebellar Cortex.
gan: Weiping Zhang, et al.
Cyhoeddwyd: (2015-01-01)

Pharmacological modulation of chloride channels as a therapeutic strategy for neurological disorders
gan: Zhiyu Wang, et al.
Cyhoeddwyd: (2023-03-01)

Pharmacological evidence of calcium-activated and voltage-gated potassium channels in human platelets.
gan: de Silva, H, et al.
Cyhoeddwyd: (1997)

Molecular and pharmacological characterization of an acetylcholine-gated chloride channel (ACC-2) from the parasitic nematode Haemonchus contortus
gan: Sarah A. Habibi, et al.
Cyhoeddwyd: (2018-12-01)

Calcium-activated chloride channel regulator 1 (CLCA1): More than a regulator of chloride transport and mucus production
gan: Cong-Lin Liu, et al.
Cyhoeddwyd: (2019-11-01)

Activation of Calcium-Activated Chloride Channels Suppresses Inherited Seizure Susceptibility in Genetically Epilepsy-Prone Rats
gan: Miracle Thomas, et al.
Cyhoeddwyd: (2022-02-01)

Presynaptic Localization and Possible Function of Calcium-Activated Chloride Channel Anoctamin 1 in the Mammalian Retina.
gan: Ji Hyun Jeon, et al.
Cyhoeddwyd: (2013-01-01)

Cobalt ion interaction with TMEM16A calcium-activated chloride channel: Inhibition and potentiation.
gan: Dung M Nguyen, et al.
Cyhoeddwyd: (2020-01-01)

Calcium-activated chloride channel regulator 1 as a prognostic biomarker in pancreatic ductal adenocarcinoma
gan: Dingyuan Hu, et al.
Cyhoeddwyd: (2018-11-01)

Specific PIP2 binding promotes calcium activation of TMEM16A chloride channels
gan: Zhiguang Jia, et al.
Cyhoeddwyd: (2021-02-01)

Vascular Response of Tetrabromobisphenol a in Rat Aorta: Calcium Channels Inhibition and Potassium Channels Activation
gan: Joana Feiteiro, et al.
Cyhoeddwyd: (2022-09-01)

Molecular mechanism underlying desensitization of the proton-activated chloride channel PAC
gan: James Osei-Owusu, et al.
Cyhoeddwyd: (2022-12-01)

Novel tricyclic pyrrolo-quinolines as pharmacological correctors of the mutant CFTR chloride channel
gan: Mario Renda, et al.
Cyhoeddwyd: (2023-05-01)

ORAI Calcium Channels: Regulation, Function, Pharmacology, and Therapeutic Targets
gan: Hussein N. Rubaiy
Cyhoeddwyd: (2023-01-01)

Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity
gan: Elisabeth E.L. Nyström, et al.
Cyhoeddwyd: (2018-07-01)

Increased Expression of the Calcium-Activated Chloride Channel in Hclca1 in Airways of Patients with Obstructive Chronic Bronchitis
gan: Hans-Peter Hauber, et al.
Cyhoeddwyd: (2005-01-01)