Understanding the molecular pharmacology of vascular calcium-activated chloride channels

Understanding the molecular pharmacology of vascular calcium-activated chloride channels

<p>Calcium-activated chloride channels (CaCCs) are a class of ion channel involved in a multitude of cellular functions. The role of CaCCs is especially well recognised in vascular smooth muscle cells (VSMCs), where CaCCs are activated by agonist-induced Ca2+ release and their opening triggers...

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Bibliografiske detaljer
Hovedforfatter:	Dinsdale, R
Andre forfattere:	Tammaro, P
Format:	Thesis
Sprog:	English
Udgivet:	2021

Lignende værker

Calcium-Activated Chloride Channels in Myometrial and Vascular Smooth Muscle
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Udgivet: (2021-10-01)

The molecular pharmacology and modulation of the proton-activated chloride channel PAC
af: Pearson, CL
Udgivet: (2023)

Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin
af: Alexandria N Miller, et al.
Udgivet: (2019-01-01)

Molecular pathology of renal chloride channels and calcium metabolism
af: Thakker, R
Udgivet: (2003)

Molecular pharmacology of kidney and inner ear CLC-K chloride channels
af: Antonella eGradogna, et al.
Udgivet: (2010-10-01)

Molecular pharmacology of native and exogenous vascular ion channels
af: Ta, C
Udgivet: (2016)

Activation and inhibition of TMEM16A calcium-activated chloride channels.
af: Yu-Li Ni, et al.
Udgivet: (2014-01-01)

Activation and Inhibition of TMEM16A Calcium-Activated Chloride Channels
af: Ni, Y, et al.
Udgivet: (2014)

Cardiac chloride channels: physiology, pharmacology and approaches for identifying novel modulators of activity.
af: Mulvaney, A, et al.
Udgivet: (2000)

TMEM16 proteins: the long awaited calcium-activated chloride channels?
af: C.A. Flores, et al.
Udgivet: (2009-11-01)

Interspecies diversity of chloride channel regulators, calcium-activated 3 genes.
af: Lars Mundhenk, et al.
Udgivet: (2018-01-01)

The Calcium-Activated Chloride Channel TMEM16A is Inhibitied by Liquiritigenin
af: Mami Kato, et al.
Udgivet: (2021-04-01)

Gating the pore of the calcium-activated chloride channel TMEM16A
af: Andy K. M. Lam, et al.
Udgivet: (2021-02-01)

Permeation Mechanisms in the TMEM16B Calcium-Activated Chloride Channels.
af: Simone Pifferi
Udgivet: (2017-01-01)

TMEM16 proteins: the long awaited calcium-activated chloride channels?
af: C.A. Flores, et al.

Molecular understanding of calcium permeation through the open Orai channel.
af: Xiaofen Liu, et al.
Udgivet: (2019-04-01)

Shikonin inhibits intestinal calcium-activated chloride channels and prevents rotaviral diarrhea
af: Yu Jiang, et al.
Udgivet: (2016-08-01)

ANO1: More Than Just Calcium-Activated Chloride Channel in Cancer
af: Saisai Guo, et al.
Udgivet: (2022-06-01)

Mechanism of pore opening in the calcium-activated chloride channel TMEM16A
af: Andy K. M. Lam, et al.
Udgivet: (2021-02-01)

A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity
af: Jason Tien, et al.
Udgivet: (2014-06-01)

Calcium-dependent electrostatic control of anion access to the pore of the calcium-activated chloride channel TMEM16A
af: Andy KM Lam, et al.
Udgivet: (2018-10-01)

Calcium-calmodulin does not alter the anion permeability of the mouse TMEM16A calcium-activated chloride channel
af: Yu, Y, et al.
Udgivet: (2014)

Spatial distribution of calcium-gated chloride channels in olfactory cilia.
af: Donald A French, et al.
Udgivet: (2010-01-01)

Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A
af: Cristina Paulino, et al.
Udgivet: (2017-05-01)

Anoctamin Calcium-Activated Chloride Channels May Modulate Inhibitory Transmission in the Cerebellar Cortex.
af: Weiping Zhang, et al.
Udgivet: (2015-01-01)

Pharmacological modulation of chloride channels as a therapeutic strategy for neurological disorders
af: Zhiyu Wang, et al.
Udgivet: (2023-03-01)

Pharmacological evidence of calcium-activated and voltage-gated potassium channels in human platelets.
af: de Silva, H, et al.
Udgivet: (1997)

Molecular and pharmacological characterization of an acetylcholine-gated chloride channel (ACC-2) from the parasitic nematode Haemonchus contortus
af: Sarah A. Habibi, et al.
Udgivet: (2018-12-01)

Calcium-activated chloride channel regulator 1 (CLCA1): More than a regulator of chloride transport and mucus production
af: Cong-Lin Liu, et al.
Udgivet: (2019-11-01)

Activation of Calcium-Activated Chloride Channels Suppresses Inherited Seizure Susceptibility in Genetically Epilepsy-Prone Rats
af: Miracle Thomas, et al.
Udgivet: (2022-02-01)

Presynaptic Localization and Possible Function of Calcium-Activated Chloride Channel Anoctamin 1 in the Mammalian Retina.
af: Ji Hyun Jeon, et al.
Udgivet: (2013-01-01)

Cobalt ion interaction with TMEM16A calcium-activated chloride channel: Inhibition and potentiation.
af: Dung M Nguyen, et al.
Udgivet: (2020-01-01)

Calcium-activated chloride channel regulator 1 as a prognostic biomarker in pancreatic ductal adenocarcinoma
af: Dingyuan Hu, et al.
Udgivet: (2018-11-01)

Specific PIP2 binding promotes calcium activation of TMEM16A chloride channels
af: Zhiguang Jia, et al.
Udgivet: (2021-02-01)

Vascular Response of Tetrabromobisphenol a in Rat Aorta: Calcium Channels Inhibition and Potassium Channels Activation
af: Joana Feiteiro, et al.
Udgivet: (2022-09-01)

Molecular mechanism underlying desensitization of the proton-activated chloride channel PAC
af: James Osei-Owusu, et al.
Udgivet: (2022-12-01)

Novel tricyclic pyrrolo-quinolines as pharmacological correctors of the mutant CFTR chloride channel
af: Mario Renda, et al.
Udgivet: (2023-05-01)

ORAI Calcium Channels: Regulation, Function, Pharmacology, and Therapeutic Targets
af: Hussein N. Rubaiy
Udgivet: (2023-01-01)

Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity
af: Elisabeth E.L. Nyström, et al.
Udgivet: (2018-07-01)

Increased Expression of the Calcium-Activated Chloride Channel in Hclca1 in Airways of Patients with Obstructive Chronic Bronchitis
af: Hans-Peter Hauber, et al.
Udgivet: (2005-01-01)