Elevated risk of invasive group A streptococcal disease and host genetic variation in the human leukocyte antigen locus

Invasive group A streptococcal (GAS) disease is uncommon but carries a high case-fatality rate relative to other infectious diseases. Given the ubiquity of mild GAS infections, it remains unclear why healthy individuals will occasionally develop life-threatening infections, raising the possibility o...

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Bibliographic Details
Main Authors: Parks, T, Elliott, K, Lamagni, T, Auckland, K, Mentzer, A, Guy, R, Cartledge, D, Strakova, L, O'Connor, D, Pollard, A, Neville, M, Mahajan, A, Ashrafian, H, Chapman, S, Hill, A, Sriskandan, S, Knight, J
Format: Journal article
Language:English
Published: Springer Nature 2019