QM/MM study on the enantioselectivity of spiroacetalization catalysed by an imidodiphosphoric acid catalyst: how confinement works.
The mechanism for the spiroacetalization of enol-ethers and promoted by chiral phosphoric acid (CPA) catalyst () and by chiral imidodiphosphoric acid catalyst () has been investigated by QM/MM methods. The computed levels of enantioselectivity following exhaustive conformational analysis is in close...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Royal Society of Chemistry
2016
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