Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer.

We conducted a genome-wide association study on 969 bladder cancer cases and 957 controls from Texas. For fast-track validation, we evaluated 60 SNPs in three additional US populations and validated the top SNP in nine European populations. A missense variant (rs2294008) in the PSCA gene showed cons...

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Bibliographic Details
Main Authors: Wu, X, Ye, Y, Kiemeney, L, Sulem, P, Rafnar, T, Matullo, G, Seminara, D, Yoshida, T, Saeki, N, Andrew, A, Dinney, C, Czerniak, B, Zhang, Z, Kiltie, A, Bishop, D, Vineis, P, Porru, S, Buntinx, F, Kellen, E, Zeegers, M, Kumar, R, Rudnai, P, Gurzau, E, Koppova, K, Mayordomo, J
Format: Journal article
Language:English
Published: 2009