Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer.

Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer.

We conducted a genome-wide association study on 969 bladder cancer cases and 957 controls from Texas. For fast-track validation, we evaluated 60 SNPs in three additional US populations and validated the top SNP in nine European populations. A missense variant (rs2294008) in the PSCA gene showed cons...

Full description

Bibliographic Details
Main Authors:	Wu, X, Ye, Y, Kiemeney, L, Sulem, P, Rafnar, T, Matullo, G, Seminara, D, Yoshida, T, Saeki, N, Andrew, A, Dinney, C, Czerniak, B, Zhang, Z, Kiltie, A, Bishop, D, Vineis, P, Porru, S, Buntinx, F, Kellen, E, Zeegers, M, Kumar, R, Rudnai, P, Gurzau, E, Koppova, K, Mayordomo, J
Format:	Journal article
Language:	English
Published:	2009

Similar Items

Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer (vol 41, pg 991, 2009)
by: Wu, X, et al.
Published: (2009)

Erratum: Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer (Nature Genetics) (2009) 41 (991-995))
by: Wu, X, et al.
Published: (2009)

ARLTS1 polymorphisms and basal cell carcinoma of the skin
by: Li Xuchen, et al.
Published: (2007-03-01)

Impact of PSCA variation on gastric ulcer susceptibility.
by: Chizu Tanikawa, et al.
Published: (2013-01-01)

Impact of PSCA Polymorphisms on the Risk of Duodenal Ulcer
by: Yoshiaki Usui, et al.
Published: (2021-01-01)

Correction: Impact of PSCA Variation on Gastric Ulcer Susceptibility
Published: (2014-01-01)

Significance of PSCA as a novel prognostic marker and therapeutic target for cancer
by: Tina Nayerpour Dizaj, et al.
Published: (2024-04-01)

PSCA is a target of chimeric antigen receptor T cells in gastric cancer
by: Di Wu, et al.
Published: (2020-01-01)

Pan-cancer analysis of PSCA that is associated with immune infiltration and affects patient prognosis.
by: Chenxing Wang, et al.
Published: (2024-01-01)

Pan-cancer analysis of PSCA that is associated with immune infiltration and affects patient prognosis
by: Chenxing Wang, et al.
Published: (2024-01-01)

Perspectives on the Plastic Surgery Common Application (PSCA): A Survey of 2021–2022 Integrated Plastic Surgery Applicants
by: Nicholas A. Elmer, BS, et al.
Published: (2023-01-01)

PSCA expression is associated with favorable tumor features and reduced PSA recurrence in operated prostate cancer
by: Marie-Christine Heinrich, et al.
Published: (2018-05-01)

PSCA is a critical biomarker for predicting the prognosis of KRAS/TP53 mutant pancreatic cancer patients
by: Mengyuan Gong, et al.
Published: (2024-09-01)

Genetic variation in PSCA and risk of gastric advanced preneoplastic lesions and cancer in relation to Helicobacter pylori infection.
by: Cosmeri Rizzato, et al.
Published: (2013-01-01)

PSCA and MUC1 in non-small-cell lung cancer as targets of chimeric antigen receptor T cells
by: Xinru Wei, et al.
Published: (2017-03-01)

Designing and validating of a questionnaire measuring perceived self-care ability (PSCA) in chronic stroke patients at home
by: Nasrin Jafari-golestan, et al.
Published: (2024-04-01)

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.
by: Rothman, N, et al.
Published: (2010)

Associations of genetic variants in the PSCA, MUC1 and PLCE1 genes with stomach cancer susceptibility in a Chinese population.
by: Hongwei Sun, et al.
Published: (2015-01-01)

Association of MUC1 5640G>A and PSCA 5057C>T polymorphisms with the risk of gastric cancer in Northern Iran
by: Reza Alikhani, et al.
Published: (2020-07-01)

PSCA-targeted BPX-601 CAR T cells with pharmacological activation by rimiducid in metastatic pancreatic and prostate cancer: a phase 1 dose escalation trial
by: Mark N. Stein, et al.
Published: (2024-12-01)

Discovery of a novel highly specific, fully human PSCA antibody and its application as an antibody-drug conjugate in prostate cancer
by: Xiaojie Chu, et al.
Published: (2024-12-01)

Transitory response to vaccination with PSCA-/PSA-peptide loaded, autologous dendritic cells in patients with metastatic, hormone-refractory prostate cancer
by: Waller CF, et al.
Published: (2004-07-01)

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
by: Stacey, SN, et al.
Published: (2011)

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility.
by: Stacey, SN, et al.
Published: (2011)

Occupational exposure to ultraviolet radiation and risk of non-melanoma skin cancer in a multinational European study.
by: Simona Surdu, et al.
Published: (2013-01-01)

Targeted RNAi of BIRC5/Survivin Using Antibody-Conjugated Poly(Propylene Imine)-Based Polyplexes Inhibits Growth of PSCA-Positive Tumors
by: Willi Jugel, et al.
Published: (2021-05-01)

Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues and its potential role in prostate carcinogenesis and progression of prostate cancer
by: Wenlv Shen, et al.
Published: (2004-05-01)

Targeted alpha therapy with astatine-211-labeled anti-PSCA A11 minibody shows antitumor efficacy in prostate cancer xenografts and bone microtumors
by: Tom A. Bäck, et al.
Published: (2020-02-01)

SNP rs2920280 in <i>PSCA</i> Is Associated with Susceptibility to Gastric Mucosal Atrophy and Is a Promising Biomarker in Japanese Individuals with <i>Helicobacter pylori</i> Infection
by: Hajime Isomoto, et al.
Published: (2022-08-01)

Construction of a fusion plasmid containing the PSCA gene and cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and its anti-tumor effect in an animal model of prostate cancer
by: T.J. Mai, et al.

Construction of a fusion plasmid containing the PSCA gene and cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and its anti-tumor effect in an animal model of prostate cancer
by: T.J. Mai, et al.
Published: (2016-10-01)

Diritto al paesaggio: considerazioni sulla disciplina vigente
by: P. Porru
Published: (2009-06-01)

On the necessity of organizing a higher theological school on the territory of the armed forces of the South of Russia: minutes of the meeting of Provisional Supreme Church Authority (PSCA) in the South-East of Russia. Introductory article and comments by Yu.A.Biryukova
by: Biryukova Yu. A.
Published: (2024-02-01)

Comprehensive analysis of 22 XPC polymorphisms and bladder cancer risk.
by: Sak, S, et al.
Published: (2006)

The polyAT, intronic IVS11-6 and Lys939Gln XPC polymorphisms are not associated with transitional cell carcinoma of the bladder.
by: Sak, S, et al.
Published: (2005)

DNA repair gene XPC polymorphisms, smoking, occupational exposures and the risk of bladder transitional cell carcinoma
by: Sak, S, et al.
Published: (2005)

DNA repair gene XRCC1 polymorphisms and bladder cancer risk
by: Sak, S, et al.
Published: (2007)

Detection of bladder cancer using proteomic profiling of urine sediments.
by: Tadeusz Majewski, et al.
Published: (2012-01-01)

The convexity of interval-functions
by: Mircea Octavian Gurzău
Published: (1976-02-01)

The convexity of interval-functions
by: Mircea Octavian Gurzău
Published: (1976-02-01)