p130Cas mediates the transforming properties of the anaplastic lymphoma kinase.

Translocations of the anaplastic lymphoma kinase (ALK) gene have been described in anaplastic large-cell lymphomas (ALCLs) and in stromal tumors. The most frequent translocation, t(2;5), generates the fusion protein nucleophosmin (NPM)-ALK with intrinsic tyrosine kinase activity. Along with transfor...

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Bibliographic Details
Main Authors: Ambrogio, C, Voena, C, Manazza, A, Piva, R, Riera, L, Barberis, L, Costa, C, Tarone, G, Defilippi, P, Hirsch, E, Boeri Erba, E, Mohammed, S, Jensen, O, Palestro, G, Inghirami, G, Chiarle, R
Format: Journal article
Language:English
Published: 2005