Regulatory T cells and organ transplantation.

Empirical studies attempting to explain tolerance to transplanted tissues have demonstrated a regulatory role for CD4+ T-cells. We here propose that regulatory T-cells mediating transplantion tolerance comprise two sets which can functionally complement each other. The CD4+CD25+ "natural regula...

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Autori principali: Waldmann, H, Graca, L, Cobbold, S, Adams, E, Tone, M, Tone, Y
Natura: Journal article
Lingua:English
Pubblicazione: 2004