A role for CD4+ but not CD8+ T cells in immunity to Schistosoma mansoni induced by 20 krad-irradiated and Ro 11-3128-terminated infections.

The role of CD4+ (L3/T4+) and CD8+ (Lyt-2+) T cells in immunity to Schistosoma mansoni induced by 20 krad-irradiated and Ro 11-terminated infections in mice was investigated directly by in vivo depletion of these subsets with cytotoxic rat monoclonal antibodies (mAb). Effective physical depletion wa...

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Bibliographic Details
Main Authors: Vignali, D, Crocker, P, Bickle, Q, Cobbold, S, Waldmann, H, Taylor, MG
Format: Journal article
Language:English
Published: 1989