Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein.

As a critical target for cyclin-dependent kinases (Cdks), the retinoblastoma tumour suppressor protein (pRb) controls early cell cycle progression. We report here a new type of regulation that influences Cdk recognition and phosphorylation of substrate proteins, mediated through the targeted methyla...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Carr, S, Munro, S, Kessler, B, Oppermann, U, La Thangue, N
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2011