Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein.
As a critical target for cyclin-dependent kinases (Cdks), the retinoblastoma tumour suppressor protein (pRb) controls early cell cycle progression. We report here a new type of regulation that influences Cdk recognition and phosphorylation of substrate proteins, mediated through the targeted methyla...
| Main Authors: | , , , , |
|---|---|
| 格式: | Journal article |
| 语言: | English |
| 出版: |
2011
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