Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein.

As a critical target for cyclin-dependent kinases (Cdks), the retinoblastoma tumour suppressor protein (pRb) controls early cell cycle progression. We report here a new type of regulation that influences Cdk recognition and phosphorylation of substrate proteins, mediated through the targeted methyla...

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書目詳細資料
Main Authors: Carr, S, Munro, S, Kessler, B, Oppermann, U, La Thangue, N
格式: Journal article
語言:English
出版: 2011