IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells.

Although very high levels of interleukin (IL)-1β are present in the intestines of patients suffering from inflammatory bowel diseases (IBD), little is known about the contribution of IL-1β to intestinal pathology. Here, we used two complementary models of chronic intestinal inflammation to address t...

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Bibliographic Details
Main Authors: Coccia, M, Harrison, O, Schiering, C, Asquith, M, Becher, B, Powrie, F, Maloy, K
Format: Journal article
Language:English
Published: 2012