The distribution of fitness effects of beneficial mutations in Pseudomonas aeruginosa.

Understanding how beneficial mutations affect fitness is crucial to our understanding of adaptation by natural selection. Here, using adaptation to the antibiotic rifampicin in the opportunistic pathogen Pseudomonas aeruginosa as a model system, we investigate the underlying distribution of fitness...

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Bibliographic Details
Main Authors: Maclean, C, Buckling, A
Format: Journal article
Language:English
Published: Public Library of Science 2009