The distribution of fitness effects of beneficial mutations in Pseudomonas aeruginosa.
Understanding how beneficial mutations affect fitness is crucial to our understanding of adaptation by natural selection. Here, using adaptation to the antibiotic rifampicin in the opportunistic pathogen Pseudomonas aeruginosa as a model system, we investigate the underlying distribution of fitness...
Hoofdauteurs: | Maclean, C, Buckling, A |
---|---|
Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
Public Library of Science
2009
|
Gelijkaardige items
-
The distribution of fitness effects of beneficial mutations in Pseudomonas aeruginosa.
door: R Craig MacLean, et al.
Gepubliceerd in: (2009-03-01) -
Diminishing returns from beneficial mutations and pervasive epistasis shape the fitness landscape for rifampicin resistance in Pseudomonas aeruginosa.
door: Maclean, C, et al.
Gepubliceerd in: (2010) -
Epistasis buffers the fitness effects of rifampicin- resistance mutations in Pseudomonas aeruginosa.
door: Hall, A, et al.
Gepubliceerd in: (2011) -
Environmental variation alters the fitness effects of rifampicin resistance mutations in Pseudomonas aeruginosa.
door: Gifford, D, et al.
Gepubliceerd in: (2016) -
Epistatic interactions between ancestral genotype and beneficial mutations shape evolvability in Pseudomonas aeruginosa.
door: Gifford, D, et al.
Gepubliceerd in: (2016)