Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) coronaviruses (CoVs) are zoonotic pathogens with high fatality rates and pandemic potential. Vaccine development focuses on the principal target of the neutralizing humoral immune response, the spike (S) glycoprotei...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Watanabe, Y, Berndsen, ZT, Raghwani, J, Seabright, GE, Allen, JD, Pybus, OG, McLellan, JS, Wilson, IA, Bowden, TA, Ward, AB, Crispin, M
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	Springer Nature 2020

Ижил төстэй зүйлс

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation
-н: Yasunori Watanabe, зэрэг
Хэвлэсэн: (2020-05-01)

Structure of the Lassa virus glycan shield provides a model for immunological resistance
-н: Watanabe, Y, зэрэг
Хэвлэсэн: (2018)

Antibodies expose multiple weaknesses in the glycan shield of HIV.
-н: Crispin, M, зэрэг
Хэвлэсэн: (2013)

Antibodies expose multiple weaknesses in the glycan shield of HIV.
-н: Crispin, M, зэрэг
Хэвлэсэн: (2013)

The impact of sequence diversity on the glycan shield of HIV-1 immunogens
-н: Seabright, GE
Хэвлэсэн: (2019)

Beyond Shielding: The Roles of Glycans in the SARS-CoV‑2 Spike Protein
-н: Lorenzo Casalino, зэрэг
Хэвлэсэн: (2020-09-01)

Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies.
-н: Pritchard, L, зэрэг
Хэвлэсэн: (2015)

Architecture of the HIV-1 glycan shield
-н: Pritchard, L
Хэвлэсэн: (2014)

Mapping the glycan shields of enveloped viruses
-н: Watanabe, Y
Хэвлэсэн: (2020)

Integrity of glycosylation processing of a glycan-depleted trimeric HIV-1 immunogen targeting key B-cell lineages
-н: Behrens, AJ, зэрэг
Хэвлэсэн: (2018)

The diversity of the glycan shield of sarbecoviruses related to SARS-CoV-2
-н: Joel D. Allen, зэрэг
Хэвлэсэн: (2023-04-01)

The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.
-н: Bonomelli, C, зэрэг
Хэвлэсэн: (2011)

Glycosylator: a Python framework for the rapid modeling of glycans
-н: Thomas Lemmin, зэрэг
Хэвлэсэн: (2019-10-01)

N- and O-glycan analysis for the detection of glycosylation disorders
-н: Amr Sobhi Gouda, зэрэг
Хэвлэсэн: (2021-01-01)

Immune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodies
-н: Le, N, зэрэг
Хэвлэсэн: (2016)

The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.
-н: Camille Bonomelli, зэрэг
Хэвлэсэн: (2011-01-01)

Fine structure of the HIV-1 glycan shield
-н: Behrens, A
Хэвлэсэн: (2017)

Glycan shield of the ebolavirus envelope glycoprotein GP
-н: Weiwei Peng, зэрэг
Хэвлэсэн: (2022-08-01)

Conformational Heterogeneity of the HIV Envelope Glycan Shield
-н: Mingjun Yang, зэрэг
Хэвлэсэн: (2017-06-01)

Glycan Nanostructures of Human Coronaviruses
-н: Guo W, зэрэг
Хэвлэсэн: (2021-07-01)

Arenavirus glycan shield promotes neutralizing antibody evasion and protracted infection.
-н: Sommerstein, R, зэрэг
Хэвлэсэн: (2015)

Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection.
-н: Rami Sommerstein, зэрэг
Хэвлэсэн: (2015-11-01)

Synthesis of N-glycan oxazolines: donors for endohexosaminidase catalysed glycosylation.
-н: Rising, T, зэрэг
Хэвлэсэн: (2006)

Editorial: Glycobiology and glycosylation: deciphering the secrets of glycans in humans and pathogens
-н: Parham Jabbarzadeh Kaboli, зэрэг
Хэвлэсэн: (2025-02-01)

N-Glycosylation and N-Glycan Processing in HBV Biology and Pathogenesis
-н: Mihaela-Olivia Dobrica, зэрэг
Хэвлэсэн: (2020-06-01)

Glycosylation network mapping and site-specific glycan maturation in vivo
-н: Marie-Estelle Losfeld, зэрэг
Хэвлэсэн: (2022-11-01)

Recognition and penetration of the HIV-1 Env glycan shield by potent broadly neutralizing antibodies
-н: Julien J, зэрэг
Хэвлэсэн: (2012-09-01)

Glycan Positioning Impacts HIV-1 Env Glycan-Shield Density, Function, and Recognition by Antibodies
-н: Qing Wei, зэрэг
Хэвлэсэн: (2020-11-01)

Antibody evasion by a gammaherpesvirus O-glycan shield.
-н: Bénédicte Machiels, зэрэг
Хэвлэсэн: (2011-11-01)

Glycan Profile Analysis of Engineered Trastuzumab with Rationally Added Glycosylation Sequons Presents Significantly Increased Glycan Complexity
-н: Esteban Cruz, зэрэг
Хэвлэсэн: (2021-10-01)

Emerging COVID-19 coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26
-н: Naveen Vankadari, зэрэг
Хэвлэсэн: (2020-01-01)

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
-н: Pejchal, R, зэрэг
Хэвлэсэн: (2011)

Glycans instructing immunity: the emerging role of altered glycosylation in clinical immunology
-н: Jonathan J Lyons, зэрэг
Хэвлэсэн: (2015-06-01)

Multivalent interactions between fully glycosylated influenza virus hemagglutinins mediated by glycans at distinct N-glycosylation sites
-н: Ruofan Li, зэрэг
Хэвлэсэн: (2024-10-01)

Fine structure of the HIV-1 glycan shield - Supplementary information
-н: Behrens, A
Хэвлэсэн: (2017)

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation
-н: Tongqing Zhou, зэрэг
Хэвлэсэн: (2017-04-01)

Glycan Shielding and Modulation of Hepatitis C Virus Neutralizing Antibodies
-н: Muriel Lavie, зэрэг
Хэвлэсэн: (2018-04-01)

Structural constraints determine the glycosylation of HIV-1 envelope trimers
-н: Pritchard, L, зэрэг
Хэвлэсэн: (2015)

Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.
-н: Rajesh P Ringe, зэрэг
Хэвлэсэн: (2023-10-01)

Controlled site-selective protein glycosylation for precise glycan structure-catalytic activity relationships.
-н: Davis, B, зэрэг
Хэвлэсэн: (2000)