Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) coronaviruses (CoVs) are zoonotic pathogens with high fatality rates and pandemic potential. Vaccine development focuses on the principal target of the neutralizing humoral immune response, the spike (S) glycoprotei...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs:	Watanabe, Y, Berndsen, ZT, Raghwani, J, Seabright, GE, Allen, JD, Pybus, OG, McLellan, JS, Wilson, IA, Bowden, TA, Ward, AB, Crispin, M
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	Springer Nature 2020

Gelijkaardige items

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation
door: Yasunori Watanabe, et al.
Gepubliceerd in: (2020-05-01)

Structure of the Lassa virus glycan shield provides a model for immunological resistance
door: Watanabe, Y, et al.
Gepubliceerd in: (2018)

Antibodies expose multiple weaknesses in the glycan shield of HIV.
door: Crispin, M, et al.
Gepubliceerd in: (2013)

Antibodies expose multiple weaknesses in the glycan shield of HIV.
door: Crispin, M, et al.
Gepubliceerd in: (2013)

The impact of sequence diversity on the glycan shield of HIV-1 immunogens
door: Seabright, GE
Gepubliceerd in: (2019)

Beyond Shielding: The Roles of Glycans in the SARS-CoV‑2 Spike Protein
door: Lorenzo Casalino, et al.
Gepubliceerd in: (2020-09-01)

Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies.
door: Pritchard, L, et al.
Gepubliceerd in: (2015)

Architecture of the HIV-1 glycan shield
door: Pritchard, L
Gepubliceerd in: (2014)

Mapping the glycan shields of enveloped viruses
door: Watanabe, Y
Gepubliceerd in: (2020)

Integrity of glycosylation processing of a glycan-depleted trimeric HIV-1 immunogen targeting key B-cell lineages
door: Behrens, AJ, et al.
Gepubliceerd in: (2018)

The diversity of the glycan shield of sarbecoviruses related to SARS-CoV-2
door: Joel D. Allen, et al.
Gepubliceerd in: (2023-04-01)

The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.
door: Bonomelli, C, et al.
Gepubliceerd in: (2011)

Glycosylator: a Python framework for the rapid modeling of glycans
door: Thomas Lemmin, et al.
Gepubliceerd in: (2019-10-01)

N- and O-glycan analysis for the detection of glycosylation disorders
door: Amr Sobhi Gouda, et al.
Gepubliceerd in: (2021-01-01)

Immune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodies
door: Le, N, et al.
Gepubliceerd in: (2016)

The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.
door: Camille Bonomelli, et al.
Gepubliceerd in: (2011-01-01)

Fine structure of the HIV-1 glycan shield
door: Behrens, A
Gepubliceerd in: (2017)

Glycan shield of the ebolavirus envelope glycoprotein GP
door: Weiwei Peng, et al.
Gepubliceerd in: (2022-08-01)

Conformational Heterogeneity of the HIV Envelope Glycan Shield
door: Mingjun Yang, et al.
Gepubliceerd in: (2017-06-01)

Glycan Nanostructures of Human Coronaviruses
door: Guo W, et al.
Gepubliceerd in: (2021-07-01)

Arenavirus glycan shield promotes neutralizing antibody evasion and protracted infection.
door: Sommerstein, R, et al.
Gepubliceerd in: (2015)

Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection.
door: Rami Sommerstein, et al.
Gepubliceerd in: (2015-11-01)

Synthesis of N-glycan oxazolines: donors for endohexosaminidase catalysed glycosylation.
door: Rising, T, et al.
Gepubliceerd in: (2006)

Editorial: Glycobiology and glycosylation: deciphering the secrets of glycans in humans and pathogens
door: Parham Jabbarzadeh Kaboli, et al.
Gepubliceerd in: (2025-02-01)

N-Glycosylation and N-Glycan Processing in HBV Biology and Pathogenesis
door: Mihaela-Olivia Dobrica, et al.
Gepubliceerd in: (2020-06-01)

Glycosylation network mapping and site-specific glycan maturation in vivo
door: Marie-Estelle Losfeld, et al.
Gepubliceerd in: (2022-11-01)

Recognition and penetration of the HIV-1 Env glycan shield by potent broadly neutralizing antibodies
door: Julien J, et al.
Gepubliceerd in: (2012-09-01)

Glycan Positioning Impacts HIV-1 Env Glycan-Shield Density, Function, and Recognition by Antibodies
door: Qing Wei, et al.
Gepubliceerd in: (2020-11-01)

Antibody evasion by a gammaherpesvirus O-glycan shield.
door: Bénédicte Machiels, et al.
Gepubliceerd in: (2011-11-01)

Glycan Profile Analysis of Engineered Trastuzumab with Rationally Added Glycosylation Sequons Presents Significantly Increased Glycan Complexity
door: Esteban Cruz, et al.
Gepubliceerd in: (2021-10-01)

Emerging COVID-19 coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26
door: Naveen Vankadari, et al.
Gepubliceerd in: (2020-01-01)

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
door: Pejchal, R, et al.
Gepubliceerd in: (2011)

Glycans instructing immunity: the emerging role of altered glycosylation in clinical immunology
door: Jonathan J Lyons, et al.
Gepubliceerd in: (2015-06-01)

Multivalent interactions between fully glycosylated influenza virus hemagglutinins mediated by glycans at distinct N-glycosylation sites
door: Ruofan Li, et al.
Gepubliceerd in: (2024-10-01)

Fine structure of the HIV-1 glycan shield - Supplementary information
door: Behrens, A
Gepubliceerd in: (2017)

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation
door: Tongqing Zhou, et al.
Gepubliceerd in: (2017-04-01)

Glycan Shielding and Modulation of Hepatitis C Virus Neutralizing Antibodies
door: Muriel Lavie, et al.
Gepubliceerd in: (2018-04-01)

Structural constraints determine the glycosylation of HIV-1 envelope trimers
door: Pritchard, L, et al.
Gepubliceerd in: (2015)

Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.
door: Rajesh P Ringe, et al.
Gepubliceerd in: (2023-10-01)

Controlled site-selective protein glycosylation for precise glycan structure-catalytic activity relationships.
door: Davis, B, et al.
Gepubliceerd in: (2000)