Mechanistic and inhibition studies on a nucleophilic cysteine protease and transpeptidases

<p>Enzymes with a nucleophilic cysteine residue catalyse important reactions in biology, including proteolysis, redox reactions, and radical transfer reactions. Nucleophilic cysteine enzymes are validated medicinal chemistry targets, e.g. thioredoxin reductase and glutathione reductase. The wo...

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Bibliographic Details
Main Author: Malla, TR
Other Authors: Schofield, C
Format: Thesis
Language:English
Published: 2022
Subjects: