GATA3 Mutations Found in Breast Cancers May Be Associated with Aberrant Nuclear Localization, Reduced Transactivation and Cell Invasiveness

GATA3 Mutations Found in Breast Cancers May Be Associated with Aberrant Nuclear Localization, Reduced Transactivation and Cell Invasiveness

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Somatic and germline mutations in the dual zinc-finger transcription factor GATA3 are associated with breast cancers expressing the estrogen receptor (ER) and the autosomal dominant hypoparathyroidism-deafness-renal dysplasia syndrome, respectively. To elucidate the role of GATA3 in breast tumorigen...

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Main Authors:	Gaynor, K, Grigorieva, I, Allen, MD, Esapa, C, Head, R, Gopinath, P, Christie, P, Nesbit, M, Jones, J, Thakker, R
格式:	Journal article
语言:	English
出版:	2013

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