GATA3 Mutations Found in Breast Cancers May Be Associated with Aberrant Nuclear Localization, Reduced Transactivation and Cell Invasiveness

Somatic and germline mutations in the dual zinc-finger transcription factor GATA3 are associated with breast cancers expressing the estrogen receptor (ER) and the autosomal dominant hypoparathyroidism-deafness-renal dysplasia syndrome, respectively. To elucidate the role of GATA3 in breast tumorigen...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Gaynor, K, Grigorieva, I, Allen, MD, Esapa, C, Head, R, Gopinath, P, Christie, P, Nesbit, M, Jones, J, Thakker, R
פורמט: Journal article
שפה:English
יצא לאור: 2013