ASPP: a new family of oncogenes and tumour suppressor genes.

The apoptosis stimulating proteins of p53 (ASPP) family consists of three members, ASPP1, ASPP2 and iASPP. They bind to proteins that are key players in controlling apoptosis (p53, Bcl-2 and RelA/p65) and cell growth (APCL, PP1). So far, the best-known function of the ASPP family members is their ab...

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Bibliographic Details
Main Authors: Sullivan, A, Lu, X
Format: Journal article
Language:English
Published: 2007