How pyroptosis contributes to inflammation and fibroblast-macrophage cross-talk in rheumatoid arthritis

About thirty years ago, a new form of pro-inflammatory lytic cell death was observed and termed pyroptosis. Only in 2015, gasdermins were defined as molecules that create pores at the plasma membrane and drive pyroptosis. Today, we know that gasdermin-mediated death is an important antimicrobial def...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Demarco, B, Danielli, S, Fischer, FA, Bezbradica, JS
Fformat: Journal article
Iaith:English
Cyhoeddwyd: MDPI 2022