ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage.
The deubiquitylation enzyme USP7/HAUSP plays a major role in regulating genome stability and cancer prevention by controlling the key proteins involved in the DNA damage response. Despite this important role in controlling other proteins, USP7 itself has not been recognized as a target for regulatio...
Κύριοι συγγραφείς: | Khoronenkova, S, Dianova, I, Ternette, N, Kessler, B, Parsons, J, Dianov, G |
---|---|
Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2012
|
Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
-
ATM-Dependent Downregulation of USP7/HAUSP by PPM1G Activates p53 Response to DNA Damage
ανά: Khoronenkova, S, κ.ά.
Έκδοση: (2012) -
Regulation of USP7/HAUSP in response to DNA damage: yet another role for ATM.
ανά: Khoronenkova, S, κ.ά.
Έκδοση: (2012) -
USP7/HAUSP stimulates repair of oxidative DNA lesions.
ανά: Khoronenkova, S, κ.ά.
Έκδοση: (2011) -
USP7/HAUSP promotes the sequence-specific DNA binding activity of p53.
ανά: Feroz Sarkari, κ.ά.
Έκδοση: (2010-09-01) -
Phosphorylation of PNKP by ATM prevents its proteasomal degradation and enhances resistance to oxidative stress.
ανά: Parsons, J, κ.ά.
Έκδοση: (2012)