Central role of reverting mutations in HLA associations with human immunodeficiency virus set point.

Much uncertainty still exists over what T-cell responses need to be induced by an effective human immunodeficiency virus (HIV) vaccine. Previous studies have hypothesized that the effective CD8(+) T-cell responses are those driving the selection of escape mutations that reduce viral fitness and ther...

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Bibliographic Details
Main Authors:	Matthews, P, Prendergast, A, Leslie, A, Crawford, H, Payne, R, Rousseau, C, Rolland, M, Honeyborne, I, Carlson, J, Kadie, C, Brander, C, Bishop, K, Mlotshwa, N, Mullins, J, Coovadia, H, Ndung'u, T, Walker, B, Heckerman, D, Goulder, P
Format:	Journal article
Language:	English
Published:	2008

Central role of reverting mutations in HLA associations with human immunodeficiency virus set point.

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