Catalytic methods for the synthesis of 1,3-disubstituted bicyclo[1.1.1]pentanes
Bicyclo[1.1.1]pentanes (BCPs) have emerged as useful bioisosteres for arenes in medicinal chemistry, demonstrating improved pharmacokinetic properties compared to the parent drugs. However, many syntheses still require the use of harsh conditions that are unsuitable for industrial applications. This...
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| Formato: | Tese |
| Idioma: | English |
| Publicado em: |
2022
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