A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency

Superparamagnetic iron oxide nanoparticles (SPIONs) have mainly been used as cellular carriers for genes and therapeutic products, while their use in subcellular organelle isolation remains underexploited. We engineered SPIONs targeting distinct subcellular compartments. Dimercaptosuccinic acid-coat...

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書誌詳細
主要な著者: Tharkeshwar, A, Trekker, J, Vermeire, W, Pauwels, J, Sannerud, R, Priestman, D, Te Vruchte, D, Vints, K, Baatsen, P, Decuypere, J, Li, H, Martin, S, Vangheluwe, P, Swinnen, J, Lagae, L, Impens, F, Platt, F, Gevaert, K, Annaert, W
フォーマット: Journal article
出版事項: Nature Publishing Group 2017