MICA expression is regulated by cell adhesion and contact in a FAK/Src-dependent manner

MICA is a major ligand for the NKG2D immune receptor, which plays a key role in activating natural killer (NK) cells and cytotoxic T cells. We analyzed NKG2D ligand expression on a range of cell types and could demonstrate that MICA expression levels were closely linked to cellular growth mode. Whil...

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Bibliographic Details
Main Authors: Moncayo, G, Lin, D, McCarthy, M, Watson, A, O'Callaghan, C
Format: Journal article
Language:English
Published: Frontiers Media 2017