MICA expression is regulated by cell adhesion and contact in a FAK/Src-dependent manner
MICA is a major ligand for the NKG2D immune receptor, which plays a key role in activating natural killer (NK) cells and cytotoxic T cells. We analyzed NKG2D ligand expression on a range of cell types and could demonstrate that MICA expression levels were closely linked to cellular growth mode. Whil...
Main Authors: | Moncayo, G, Lin, D, McCarthy, M, Watson, A, O'Callaghan, C |
---|---|
Format: | Journal article |
Sprog: | English |
Udgivet: |
Frontiers Media
2017
|
Lignende værker
-
Reduced glucose availability lowers MICA expression: a possible mechanism for tumour immune-evasion
af: McCarthy, M, et al.
Udgivet: (2011) -
Purine nucleotide metabolism regulates expression of the human immune ligand MICA
af: McCarthy, MT, et al.
Udgivet: (2017) -
Leptin induces cell migration and invasion in a FAK-Src-dependent manner in breast cancer cells
af: Juan Carlos Juárez-Cruz, et al.
Udgivet: (2019-12-01) -
Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility
af: Wang Wenqi, et al.
Udgivet: (2011-11-01) -
Signal Transduction Mechanisms of Focal Adhesions: Src and FAK-Mediated Cell Response
af: Kazuo Katoh
Udgivet: (2024-11-01)