The behavioural and molecular characterisation of a novel LRRK2 BAC transgenic rat model of Parkinson’s disease
<p>Mutations in the leucine-rich repeat kinase II (<em>LRRK2</em>) gene cause autosomal-dominant Parkinson’s disease (PD) which is indistinguishable from sporadic forms of the disease. However, the mechanism by which <em>LRRK2</em> mutation promotes PD pathology and the...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
2014
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| Subjects: |