The behavioural and molecular characterisation of a novel LRRK2 BAC transgenic rat model of Parkinson’s disease

<p>Mutations in the leucine-rich repeat kinase II (<em>LRRK2</em>) gene cause autosomal-dominant Parkinson’s disease (PD) which is indistinguishable from sporadic forms of the disease. However, the mechanism by which <em>LRRK2</em> mutation promotes PD pathology and the...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Sloan, M, Maximilian Sloan
Awduron Eraill: Wade-Martins, R
Fformat: Traethawd Ymchwil
Iaith:English
Cyhoeddwyd: 2014
Pynciau: