The behavioural and molecular characterisation of a novel LRRK2 BAC transgenic rat model of Parkinson’s disease

<p>Mutations in the leucine-rich repeat kinase II (<em>LRRK2</em>) gene cause autosomal-dominant Parkinson’s disease (PD) which is indistinguishable from sporadic forms of the disease. However, the mechanism by which <em>LRRK2</em> mutation promotes PD pathology and the...

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Bibliografiska uppgifter
Huvudupphovsmän: Sloan, M, Maximilian Sloan
Övriga upphovsmän: Wade-Martins, R
Materialtyp: Lärdomsprov
Språk:English
Publicerad: 2014
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