The behavioural and molecular characterisation of a novel LRRK2 BAC transgenic rat model of Parkinson’s disease

<p>Mutations in the leucine-rich repeat kinase II (<em>LRRK2</em>) gene cause autosomal-dominant Parkinson’s disease (PD) which is indistinguishable from sporadic forms of the disease. However, the mechanism by which <em>LRRK2</em> mutation promotes PD pathology and the...

詳細記述

書誌詳細
主要な著者: Sloan, M, Maximilian Sloan
その他の著者: Wade-Martins, R
フォーマット: 学位論文
言語:English
出版事項: 2014
主題: