The behavioural and molecular characterisation of a novel LRRK2 BAC transgenic rat model of Parkinson’s disease
<p>Mutations in the leucine-rich repeat kinase II (<em>LRRK2</em>) gene cause autosomal-dominant Parkinson’s disease (PD) which is indistinguishable from sporadic forms of the disease. However, the mechanism by which <em>LRRK2</em> mutation promotes PD pathology and the...
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| 格式: | Thesis |
| 語言: | English |
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2014
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