In vivo and in situ replication labeling methods for super-resolution structured illumination microscopy of chromosome territories and chromatin domains

Recent advances in super-resolution microscopy enable the study of subchromosomal chromatin organization in single cells with unprecedented detail. Here we describe refined methods for pulse-chase replication labeling of individual chromosome territories (CTs) and replication domain units in mammali...

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Bibliographic Details
Main Authors: Miron, E, Innocent, C, Heyde, S, Schermelleh, L
Format: Journal article
Language:English
Published: Springer New York 2016