In vivo and in situ replication labeling methods for super-resolution structured illumination microscopy of chromosome territories and chromatin domains
Recent advances in super-resolution microscopy enable the study of subchromosomal chromatin organization in single cells with unprecedented detail. Here we describe refined methods for pulse-chase replication labeling of individual chromosome territories (CTs) and replication domain units in mammali...
Main Authors: | Miron, E, Innocent, C, Heyde, S, Schermelleh, L |
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Format: | Journal article |
Language: | English |
Published: |
Springer New York
2016
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