Molecular modeling of the bisphosphonates in farnesyl diphosphate synthase. potential new details of the precise biochemical mechanism of action of potent nitrogen containing bisphosphonates

Geahča maid

• Modeling of bisphosphonate binding to farnesyl diphosphate synthase
  Dahkki: Ebetino, F, et al.
  Almmustuhtton: (2002)
• Molecular modeling of the bisphosphonates (BPs) in farnesyl diphosphate (FPP) synthase. Proposed new mechanism of inhibition by potent nitrogen containing bisphosphonates (NBPs).
  Dahkki: Ebetino, F, et al.
  Almmustuhtton: (2002)
• Molecular interactions of nitrogen-containing bisphosphonates within farnesyl diphosphate synthase
  Dahkki: Ebetino, F, et al.
  Almmustuhtton: (2005)
• Investigations into the kinetic mechanism of inhibition of farnesyl diphosphate synthase by nitrogen containing bisphosphonates
  Dahkki: Dunford, J, et al.
  Almmustuhtton: (2006)
• Predicting the clinical potencies of bisphosphonates: Divergence of hydroxyapatite and farnesyl diphosphate synthase binding affinities
  Dahkki: Xia, Z, et al.
  Almmustuhtton: (2007)