Association of human corticotropin-releasing hormone to its binding protein in blood may trigger clearance of the complex.

Late in the last trimester of human pregnancy, as plasma CRH levels rise, the concentration of circulating CRH-binding protein (CRH-BP) falls. We have investigated, using nonpregnant subjects, the hypothesis that CRH has a negative effect on plasma levels of CRH-BP. A specific RIA developed with the...

Full description

Bibliographic Details
Main Authors: Woods, R, Grossman, A, Saphier, P, Kennedy, K, Ur, E, Behan, D, Potter, E, Vale, W, Lowry, P
Format: Journal article
Language:English
Published: 1994