Tandem copper-catalysed aryl and alkenyl amination reactions: the synthesis of N-functionalised indoles.

Tandem copper-catalysed aryl and alkenyl amination reactions: the synthesis of N-functionalised indoles.

A Cu-diamine complex effectively catalyses tandem C-N bond formation on 2-(2-haloalkenyl)-aryl halide substrates, to deliver a series of N-functionalised indoles. Anilines, amides and carbamates are all effective coupling partners under the developed conditions.

书目详细资料
Main Authors:	Hodgkinson, R, Schulz, J, Willis, M
格式:	Journal article
语言:	English
出版:	2009

相似书籍

Palladium-catalysed tandem alkenyl- and aryl-C-N bond formation: a cascade N-annulation route to 1-functionalised 7-azaindoles
由: Hodgkinson, R, et al.
出版: (2009)

Copper-catalysed benzofuran synthesis: developing aryl bromide-alkenyl triflates as general heterocycle precursors
由: Tadd, A, et al.
出版: (2007)

Palladium-catalysed aminosulfonylation of aryl-, alkenyl- and heteroaryl halides: scope of the three-component synthesis of N-aminosulfonamides.
由: Emmett, E, et al.
出版: (2012)

Palladium-catalyzed tandem alkenyl and aryl C--N bond formation: a cascade N-annulation route to 1-functionalized indoles.
由: Willis, M, et al.
出版: (2005)

2-(2-haloalkenyl)-aryl halides as substrates for palladium-catalysed tandem C-N bond formation: Efficient synthesis of 1-substituted indoles
由: Willis, M, et al.
出版: (2006)

Computational exploration of the reaction mechanism of the Cu+-catalysed synthesis of indoles from N-aryl enaminones
由: Carlos E. P. Bernardo, et al.
出版: (2016-01-01)

DFT calculations on the mechanism of copper-catalysed tandem arylation–cyclisation reactions of alkynes and diaryliodonium salts
由: Tamás Károly Stenczel, et al.
出版: (2018-07-01)

Rhodium(II)-catalysed tandem aziridination and ring-opening: stereoselective synthesis of functionalised tetrahydrofurans.
由: Unsworth, W, et al.
出版: (2014)

Palladium- and Copper-Catalyzed Aryl Halide Amination, Etherification and Thioetherification Reactions in the Synthesis of Aromatic Heterocycles
由: Sadig, J, et al.
出版: (2011)

Gold-catalysed functionalisations of yndiamides
由: Tong, Z
出版: (2023)

Intramolecular palladium-catalyzed direct arylation of alkenyl triflates.
由: Cruz, A, et al.
出版: (2007)

Palladium-catalysed addition of aryl halides to N-sulfinylamines for the synthesis of sulfinamides
由: Wei, M-K, et al.
出版: (2024)

A rhodium-catalysed Sonogashira-type coupling exploiting C–S functionalisation: orthogonality with palladium-catalysed variants
由: Arambasic, M, et al.
出版: (2019)

Palladium catalyzed tandem alkenyl- and aryl-C-N bond formation: a cascade N-annulation route to 4-, 5-, 6-and 7-chloroindoles
由: Henderson, L, et al.
出版: (2010)

Cascade palladium-catalyzed alkenyl aminocarbonylation/ intramolecular aryl amidation: an annulative synthesis of 2-quinolones.
由: Tadd, A, et al.
出版: (2009)

Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles.
由: Hamed, R, et al.
出版: (2010)

Palladium catalysed aryl enol ether synthesis from vinyl triflates.
由: Willis, M, et al.
出版: (2003)

Copper-catalysed regioselective sulfenylation of indoles with sodium sulfinates
由: Xiaojun Luo, et al.
出版: (2018-01-01)

Enantioselective synthesis of α-aminoboronates by NiH-catalysed asymmetric hydroamidation of alkenyl boronates
由: Yao Zhang, et al.
出版: (2022-09-01)

Challenging nickel-catalysed amine arylations enabled by tailored ancillary ligand design
由: Christopher M. Lavoie, et al.
出版: (2016-03-01)

Palladium-catalysed N-annulation routes to indoles: the synthesis of indoles with sterically demanding N-substituents, including demethylasterriquinone A1.
由: Fletcher, A, et al.
出版: (2007)

Palladium-catalysed enolate arylation in the synthesis of isoquinolines
由: Gatland, A, et al.
出版: (2014)

Copper-catalysed autocatalytic reactions
由: Post, E
出版: (2020)

Photocatalytic reductive synthesis of α-functionalised amines and ethers
由: Rossolini, T
出版: (2021)

Synthesis of heterocycles via palladium-catalysed direct arylation
由: Yagoubi, M
出版: (2011)

Palladium-catalysed intramolecular enolate O-arylation and thio-enolate S-arylation: synthesis of benzo[b]furans and benzo[b]thiophenes
由: Willis, M, et al.
出版: (2006)

Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents
由: Christopher Beattie, et al.
出版: (2011-04-01)

Directed C–H alkenylation of aryl imines with alkenyl phosphates promoted by a cobalt–N‐heterocyclic carbene catalyst
由: Lee, Pin-Sheng, et al.
出版: (2019)

One-pot three-component sulfone synthesis exploiting palladium-catalysed aryl halide aminosulfonylation
由: Richards-Taylor, C, et al.
出版: (2014)

Photoinduced site-selective alkenylation of alkanes and aldehydes with aryl alkenes
由: Hui Cao, et al.
出版: (2020-04-01)

Copper-catalyzed N-arylation of amines with aryliodonium ylides in water
由: Kasturi U. Nabar, et al.
出版: (2023-07-01)

Aryl acrylonitriles synthesis enabled by palladium-catalyzed α-alkenylation of arylacetonitriles with vinyl halides/triflates
由: Yonggang Jiang, et al.
出版: (2022-12-01)

Bifunctional iminophosphorane catalysed enantioselective sulfa-Michael addition of alkyl thiols to alkenyl benzimidazoles
由: Formica, M, et al.
出版: (2018)

Copper-catalyzed O-alkenylation of phosphonates
由: Nuria Vázquez-Galiñanes, et al.
出版: (2020-04-01)

Synthesis of 3-alkenylindoles through regioselective C–H alkenylation of indoles by a ruthenium nanocatalyst
由: Abhijit Paul, et al.
出版: (2020-01-01)

Copper-catalysed selective hydroamination reactions of alkynes
由: Shi, Shi-Liang, et al.
出版: (2015)

Development of copper-catalysed addition reactions to alkynes
由: Tan, QW
出版: (2019)

Synthesis of Nitroarenes by Oxidation of Aryl Amines
由: Antonella Capperucci, et al.
出版: (2022-02-01)

Palladium- and copper-catalysed heterocycle synthesis
由: Ball, C
出版: (2014)

An efficient copper-catalysed pyrrole synthesis
由: Damian G. Dunford, et al.
出版: (2012-09-01)