Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man.

The steady-state basal plasma glucose and insulin concentrations are determined by their interaction in a feedback loop. A computer-solved model has been used to predict the homeostatic concentrations which arise from varying degrees beta-cell deficiency and insulin resistance. Comparison of a patie...

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Bibliographic Details
Main Authors: Matthews, DR, Hosker, J, Rudenski, A, Naylor, B, Treacher, D, Turner, R
Format: Journal article
Language:English
Published: Springer-Verlag 1985