Ewing sarcoma cells express RANKL and support osteoclastogenesis.

Ewing sarcoma (ES) is a primary malignant round cell tumour of bone characterized by rapid and extensive osteolysis. Cellular mechanisms underlying the rapid bone resorption in ES have not been characterized. Osteoclasts are marrow-derived multinucleated cells that effect tumour osteolysis. The role...

詳細記述

書誌詳細
主要な著者: Taylor, R, Knowles, H, Athanasou, N
フォーマット: Journal article
言語:English
出版事項: 2011