Ewing sarcoma cells express RANKL and support osteoclastogenesis.
Ewing sarcoma (ES) is a primary malignant round cell tumour of bone characterized by rapid and extensive osteolysis. Cellular mechanisms underlying the rapid bone resorption in ES have not been characterized. Osteoclasts are marrow-derived multinucleated cells that effect tumour osteolysis. The role...
প্রধান লেখক: | , , |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
2011
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