Ewing sarcoma cells express RANKL and support osteoclastogenesis.

Ewing sarcoma (ES) is a primary malignant round cell tumour of bone characterized by rapid and extensive osteolysis. Cellular mechanisms underlying the rapid bone resorption in ES have not been characterized. Osteoclasts are marrow-derived multinucleated cells that effect tumour osteolysis. The role...

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Main Authors: Taylor, R, Knowles, H, Athanasou, N
格式: Journal article
语言:English
出版: 2011